Sodium Hyaluronate Eye Drops Instructions
Release time:
2020-07-07
Approval Date: May 21, 2007
Revision Date: December 21, 2010
Peak
Sodium Hyaluronate Eye Drops Instructions
[Drug Name]
General Name: Sodium Hyaluronate Eye Drops
English Name: Sodium Hyaluronate Hyaluronate Eye Drops
Chinese Pinyin: Bolisuanna Diyanye
[Ingredients]
The main ingredient of this product is sodium hyaluronate.
Chemical Name:(1 → 4)-O-β-D-Glucuronic Acid-(1 → 3)-2-Acetylamino -2-Deoxy-β-D-Glucose
Molecular Formula:(C14H20NNaO11)n
[Character] This product is a colorless and clear slightly viscous liquid.
[Indications]
is used for keratoconjunctival epithelial injury caused by internal diseases such as Sjogren's syndrome (Sjogren,s syndrome), Sjogren's syndrome (Stevens-Johnson syndrome), dry eye (dry eye) and various external diseases (such as surgery, drug-induced, trauma, wearing contact lenses, etc.). It is especially suitable for patients with Sjogren's syndrome and Sjogren's syndrome requiring long-term medication.
[Specification] 5ml:5mg(0.1%)
[Usage and Dosage]
Eye drops, usually 1 drop at a time, 5-6 times a day, can be appropriately increased or decreased according to symptoms. Generally, 0.1% of the preparation is used, and 0.3% of the preparation is used in cases where the effect is not good.
[Adverse Reactions]
(1) Sometimes corneal disorders such as itching, irritation, congestion, and diffuse superficial keratitis may occur. If the above symptoms occur, the medication should be stopped immediately.
(2) Allergy: Occasional blepharitis, blepharitis and other allergic symptoms, such as allergy, should immediately stop medication.
[Taboo] is not clear.
[Precautions]
This product is only used for eye drops. Be careful not to contact the mouth of the eye drop bottle with the eye when dropping the eye. Please close the bottle cap tightly after use. After opening, do not use the soft contact lens without removing it.
[Use in pregnant and lactating women] is not clear.
Pediatric use is not clear.
[Geriatric use] is not clear.
Drug interaction is not clear.
Overdose is unknown.
[Pharmacology and Toxicology]
Sodium hyaluronate is a natural polymer compound, which is an important component of tissue matrix. It has good viscoelasticity and has a protective effect on cornea. Combined with fibronectin, it promotes the connection and extension of corneal epithelial cells and accelerates corneal wound healing. In addition, sodium hyaluronate molecules have strong hydrophilic ability and lubrication, which can stabilize the tear film, prevent keratoconjunctival dryness and reduce the friction of eye tissue, and relieve the discomfort symptoms of dry eye.
[Pharmacokinetics]
After 14C-labeled 0.1 sodium hyaluronate eye drops are instilled in rabbits, strong radioactivity can be detected in conjunctiva, external eye muscle and sclera within 0.5h, with the strongest radioactivity in conjunctiva, weak radioactivity can be detected in cornea, retina and choroid, while no radioactivity can be detected in aqueous humor, iris, ciliary body, crystal and vitreous. The radioactivity of the conjunctiva dropped below the threshold after 24h. Healthy people were given 0.1 sodium hyaluronate eye drops on the first day of monocular eyes, and were changed to 0.5 sodium hyaluronate eye drops on the second day, 1 drop once, 5 times a day, and continued to use sodium hyaluronate eye drops on the third to ninth days, 13 times a day, for 7 consecutive days. The concentration of sodium hyaluronate in serum was determined at the beginning of the drop, on the third day, the ninth day and the tenth day, and all of them were below the detection limit (10?g/ml), which was the same as that of the drop.
[Storage] Shade and place in a cool place (not more than 20 ℃).
[packaging] plastic bottles, 5ml per bottle.
[Validity Period] 24 Months
[Implementation Standard] YBH04002006
[Approval Document Number] National Medicine Standard H20063950
[Production Enterprise]
Enterprise Name: Zhejiang Jianfeng Pharmaceutical Co., Ltd.
Address: 368 Jinqu Road, Jinhua Industrial Park, Zhejiang Province Zip Code: 321016
Tel: 0579-82273183
Fax: 0579-82272272
Website:
www.zjjy.com.cn
More information
Spike Health was identified as Zhejiang Agricultural Science and Technology R & D Center
Zhejiang Provincial Department of science and technology recently issued a notice, peak health technology company research and development center was identified as Zhejiang agricultural science and technology research and development center. According to the relevant requirements, Zhejiang agricultural science and technology research and development center must be established with national and provincial agricultural leading enterprises, agricultural science and technology enterprises or other scientific and technological agricultural enterprises with high scientific and technological content as the carrier, with strong economic strength and scientific and technological research and development foundation; The annual sales income of the enterprise is more than 10 million yuan, and the R & D center has more than 10 full-time technicians, of whom more than 30% have bachelor's degree or above; the annual technology development funds shall not be less than 3% of the sales revenue of the enterprise; it has the necessary instruments and equipment and fixed and special places to meet the research and development; it has the conditions for the application of agricultural technology information network. The main business of the enterprise is clear, and it is the priority industry in our province. The technological innovation achievements have a wide range of radiation, the enterprise system is sound, and the operating mechanism is good. With the domestic, provincial institutions of higher learning, scientific research units have established a stable relationship of scientific research cooperation. Since its establishment, Jianfeng Health has attached great importance to the construction of innovation platform and the cultivation of scientific and technological talents. In 2016, it has been recognized as Jinhua agricultural science and technology enterprise and municipal agricultural science and technology research and development center. In 2017, research and development investment accounted for 5.06 of sales revenue, and full-time research and development personnel with bachelor's degree or above accounted for 80.9, consisting of talents including traditional Chinese medicine, traditional Chinese medicine preparation, agriculture and biotechnology, pharmacy, analysis, plant extraction, food engineering, etc. Dr. Li Wende, head of the research and development center, was also selected "Jinhua Shuanglong plan talent" in 2017 ". In recent years, peak health and Zhejiang workers.
2020
07-31
Chairman Jiang Xiaomeng Directs Work in Yunnan Peak
On December 16, Jiang Xiaomeng, Secretary of the Party committee and chairman of the group company, went to Yunnan Jianfeng cement company to investigate and guide the work. On the morning of the same day, accompanied by the Yunnan peak management team, Jiang Xiaomeng went deep into the front line and successively went to the central control room of the production and manufacturing department, the raw material clay yard, the lignite yard and other areas for field investigation and investigation to understand the problems existing in the production and operation process. Subsequently, a business analysis meeting was held to make a comparative analysis of the various business indicators of Yunnan Jianfeng from January to November this year, and put forward two requirements to the management team: further strengthen internal management and improve execution; strengthen the coordination of external relations, and improve The ability and level of enterprise resource acquisition. At the Yunnan Jianfeng middle-level cadre meeting held on the afternoon of the 16th, Jiang Xiaomeng first fully affirmed Yunnan Jianfeng's highest output and best benefits since it was put into production in 2018, and expressed his gratitude to all cadres and employees of Yunnan Jianfeng for their hard work. After that, Jiang Xiaomeng made a detailed analysis of the cement industry and the regional market environment in Yunnan, and combined with the current production and operation situation of Yunnan Jianfeng, put forward the focus of the next step: 1. should fully attach importance to and mobilize the initiative and responsibility of employees at all levels to improve the overall execution of the team; 2. raw material mines are an important factor restricting the future development of cement enterprises, which should be paid full attention to and formulate clear strategies and methods, set out a timetable to obtain future production resources as much as possible; 3. continuously advocate and promote technological innovation, keep pace with the times, continuously improve production management, equipment management, production technology level, and maintain the competitive advantage of the industry; 4. further strengthen production
2020
07-31
Chairman Jiang Xiaomeng Directs Work in Yunnan Peak
On December 16, Jiang Xiaomeng, Secretary of the Party committee and chairman of the group company, went to Yunnan Jianfeng cement company to investigate and guide the work. On the morning of the same day, accompanied by the Yunnan peak management team, Jiang Xiaomeng went deep into the front line and successively went to the central control room of the production and manufacturing department, the raw material clay yard, the lignite yard and other areas for field investigation and investigation to understand the problems existing in the production and operation process. Subsequently, a business analysis meeting was held to make a comparative analysis of the various business indicators of Yunnan Jianfeng from January to November this year, and put forward two requirements to the management team: further strengthen internal management and improve execution; strengthen the coordination of external relations, and improve The ability and level of enterprise resource acquisition. At the Yunnan Jianfeng middle-level cadre meeting held on the afternoon of the 16th, Jiang Xiaomeng first fully affirmed Yunnan Jianfeng's highest output and best benefits since it was put into production in 2018, and expressed his gratitude to all cadres and employees of Yunnan Jianfeng for their hard work. After that, Jiang Xiaomeng made a detailed analysis of the cement industry and the regional market environment in Yunnan, and combined with the current production and operation situation of Yunnan Jianfeng, put forward the focus of the next step: 1. should fully attach importance to and mobilize the initiative and responsibility of employees at all levels to improve the overall execution of the team; 2. raw material mines are an important factor restricting the future development of cement enterprises, which should be paid full attention to and formulate clear strategies and methods, set out a timetable to obtain future production resources as much as possible; 3. continuously advocate and promote technological innovation, keep pace with the times, continuously improve production management, equipment management, production technology level, and maintain the competitive advantage of the industry; 4. further strengthen production
2020
07-30
Editor's note: On November 20, the first page of "Jinhua Daily" published "Focus on sticking to the peak forever-Enlightenment of Jianfeng Group's 60 years of entrepreneurship" written by the reporter of the newspaper, which was specially reprinted by this newspaper. Focus on sticking to the peak forever-Jianfeng Group's 60 years of entrepreneurship enlightenment "Jinhua Daily" reporter Shao Xuilian as of the end of the third quarter of this year, the total assets of 4.788 billion yuan, net assets of 3.366 billion yuan, the realization of the parent company's net profit of 0.488 billion yuan, earnings per share of 1.42 yuan. Recently, Jianfeng Group disclosed its beautiful report for the third quarter of 2018, celebrating its 60th anniversary with the best operating results in history. Wind and rain for 60 years. With sustained and steady high-quality development, the peak people are moving towards a comprehensive modern enterprise group with strong core competitiveness. Strategy: Focus and Professionalism In 1958, the first generation of peak people built the first cement factory in Jinhua history at the foot of peak mountain. Beginning in 1983, through horizontal alliances with township enterprises, the formation of enterprise groups, and the implementation of shareholding reforms, Jianfeng has developed from a small state-owned cement plant to the first listed company in China's cement industry. Since then, in the stage of diversification, the peak will develop the pharmaceutical industry into the second pillar industry. In 2007, it joined forces with the central enterprise China Building Materials to participate in the establishment of Southern Cement and strategically shifted the focus of the cement industry; at the same time, through corporate mergers and acquisitions and technological innovation, the pharmaceutical industry has further exerted its strength. Today, Jianfeng Group has 33 participating and holding subsidiaries, involving building materials, medicine, big health, modern logistics, national.
2020
07-31
News from our newspaper On the occasion of the celebration of the 60th anniversary of Jianfeng's entrepreneurship, the selection results of the two competitions of "Me and Jianfeng" essay and employee calligraphy and painting photography exhibition are also fresh. Since July 2017, more than 50 contributions have been received from employees and their families. According to the overall situation of the content and writing level of the solicitation, 3 first prize works, 5 second prize works and 7 third prize works were selected. The staff calligraphy and painting photography exhibition began to call for contributions in early April. in just five months, it received more than 100 works from dozens of authors from various enterprises under the group, and successfully held the exhibition from October 10 to 17, which was welcomed and praised by the majority of employees. After a comprehensive selection of employee contributions, a total of 3 first-class works, 5 second-class works, and 7 third-class works were selected. In order to ensure the fairness and impartiality of the selection, the works of the leading group, working group members and specially invited works to commemorate the 60th anniversary of Jianfeng Entrepreneurship will not participate in the selection of the grade award. (The list of winners is attached) (This reporter) "I and the peak" essay list first prize "mother and son deep love" author: Daye peak Shi Fu "I have a date with the peak" author: Yunnan peak Luo Meiyan "buying a house" author: peak cable Lu Chaofang second prize "ten years, sixty years" author: pharmaceutical sales company Xu Yuting "my peak road" author: daye Peak Yang Zhendong's "My Teacher" Author: Fan Tufa, Municipal Pharmaceutical Company, "Peak Grows with Me for 20 Years" Author: Xu Junxiong, Pharmaceutical Sales Company, "Peak Grows with Me"
2020
07-31
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