Azithromycin Sulfate for Injection Instructions
Release time:
2020-07-31
Approval Date: March 29, 2007
First Amendment Date: November 13, 2007
Second Amendment Date: October 31, 2014
-dimensional Ruth
Azithromycin Sulfate Instructions
Please read the instructions carefully and use them under the guidance of doctors.
[Drug Name]
Common Name: Azithromycin Sulfate for Injection
Trade Name: Verude
English Name: Azithromycin Sulfate for Injection
Chinese Pinyin: ZhusheyongLiusuan Aqimeisu
[Ingredients] The main ingredient of this product is azithromycin sulfate, and its chemical name is: 9-deoxy -9 α-aza -9 α-methyl -9 α-erythromycin A sulfate.
Chemical Structural Formula:
Molecular Formula: C38H72N2012 H2S04
Molecular Weight: 847.00
[Character] This product is white or almost white loose block or powder.
[indications] 1, for acute pharyngitis caused by Streptococcus pyogenes, acute tonsillitis.
2. For pneumonia caused by Streptococcus pneumoniae, influenza bacillus and Mycoplasma pneumoniae.
3, for chlamydia caused by urethritis and cervicitis.
4. It is used for acute bronchitis and acute attack of chronic bronchitis caused by sensitive bacteria.
5. For skin and soft tissue infections caused by sensitive bacteria.
[Specifications] 0.25g (250000 units) and 0.5g (500000 units) (calculated by C38H72N2012)
[Usage and Dosage] Fully dissolve the product with appropriate amount of water for injection to prepare a solution containing 0.1g per 1ml, then add it to 250ml or 500ml of 0.9 sodium chloride injection or 5% glucose injection, and the final azithromycin concentration is 1.0-2.0 mg/ml for intravenous drip, instillation time: 1 mg/ml, instillation for 3 hours; 2 mg/ml, instillation for 1 hour. For the treatment of community-acquired pneumonia, the adult dosage is 0.5g each time, once a day, for at least 2 consecutive days. Next, azithromycin oral preparation 0.5g/day, 7-10 days of treatment for a course of treatment. The timing of conversion to oral therapy should be determined by the physician based on clinical response. For the treatment of pelvic inflammatory disease, the adult dosage is 0.5g each time, once a day. After 1 day or 2 days of medication, azithromycin oral preparation O.25g is used instead, with 7 days as a course of treatment. The timing of conversion to oral therapy should be determined by the physician based on clinical response. If an anaerobic infection is suspected, an anti-anaerobic drug should be used.
[adverse reactions] occasionally can appear dizziness, headache and fever, rash, joint pain and other allergic reactions, rare anaphylactic shock and angioedema. A few patients may have transient neutropenia and elevated serum aminotransferase.
[taboo] to erythromycin or other macrolide drug allergy is prohibited.
[Precautions] Patients with liver damage should use this product with caution.
[medication for pregnant and lactating women] animal experiments have shown that azithromycin has no effect on the fetus, but it is still lack of experience in the application of human pregnant women, so it is necessary to fully weigh the pros and cons in the application of pregnant women.
There is no information on whether azithromycin can be secreted into breast milk, and the use of azithromycin in lactating women should be considered with caution.
[Children's medication] The dosage and administration method for children under 6 months of age have not been established. Efficacy and safety for the treatment of otitis media in infants less than 6 months of age, community-acquired pneumonia, and pharyngitis or tonsillitis in children less than 2 years of age have not been established.
[Geriatric use] This experiment has not been performed and there are no reliable references.
[Drug Interactions] l. When combined with aminophylline, attention should be paid to monitoring the blood concentration of the latter.
2, and warfarin should pay attention to check the prothrombin time.
3, combined with carbamazepine and digoxin, can increase the blood concentration of carbamazepine and digoxin.
[Overdose] This experiment was not performed and there are no reliable references.
[Pharmacology and Toxicology] Azithromycin is a 15-member ring macrolide, the first variety of nitrogen lactones. Its mechanism of action is the same as that of erythromycin, which mainly binds to the 50s subunit of bacterial ribosome and inhibits RNA-dependent protein synthesis. This product has good antibacterial effect on Streptococcus pyogenes, Streptococcus pneumoniae and influenza bacillus, and also has antibacterial activity on Staphylococcus. This product on Staphylococcus, Streptococcus and other Gram-positive cocci antibacterial effect is slightly worse than erythromycin on influenza bacilli and Moraxella catarrh antibacterial effect than erythromycin 4~8 times and 2~4 times, on a small number of Escherichia coli, Salmonella, Shigella can also have antibacterial effect. This product has good antimicrobial effect on anaerobic bacteria such as digestive streptococcus, mycoplasma pneumoniae and chlamydia trachomatis.
[Pharmacokinetics] This product is widely distributed in the body, and its concentration in various tissues can reach l0 ~ 100 times of the blood drug concentration in the same period. This product has high concentration in macrophages and fibroblasts, the former can transport azithromycin to the site of inflammation. The half-life (tl/2) of azithromycin after a single dose is 35-48 hours, more than 50% of the dose is excreted through the biliary tract in the original form, and about 4.5 within 72 hours after administration is excreted in the original form with urine.
[Storage] Closed and stored in a cool place (not more than 20 ℃).
[Packaging] Glass bottles, 0.25g × 2 bottles/box, 0.25g × 1 bottle/box, 0.25g × 10 bottles/box, 0.5g × 1 bottle/box, 0.5g × 10 bottles/box.
[validity] tentatively 24 months.
[Implementation Standard] WS-359(X-305)-2002(1)(0.25g);WS-359(X-305)-2002(2)(0.5g)
[Approval Document No.] H20000728(0.25g), H20000729(0.5g).
[Production Enterprise]
Enterprise Name: Zhejiang Jianfeng Pharmaceutical Co., Ltd.
Address: No. 58, Gaofan Section, Baitang Downline, Wucheng District, Jinhua City, Zhejiang Province
Tel: 0579-82661998 (Consultation) 0579-82131973 (Sales)
Fax Number: 0579-82661998 Postal Code: 321075
Website: www.zjjfyy.com.cn
More information
Two Cement Enterprises Start to Implement "Big Patrol Inspection"
With the change of the competition situation in the industry, the profit space of cement production enterprises has been greatly squeezed. Reducing costs and increasing efficiency and job optimization have become the inevitable choice to improve the enterprise's own development ability and enhance the core competitiveness. In accordance with the requirements of the group company to realize the transformation from extensive management to lean management, combined with the advanced experience of peer enterprises, recently, Yunnan peak, daye peak two enterprises have implemented "big inspection" to promote the overall optimization of posts. On November 1, daye peak post inspection officially started full operation, starting from the limestone storage yard at the source of the production line to the cement storage. the original 15 posts were merged, and the best experienced mechanics, electricians and post workers were transferred to form a large inspection class, which was mainly responsible for on-site emergency disposal and post routine maintenance to ensure the normal production of the whole production line. In order to ensure the smooth implementation of the large-scale inspection, daye peak management team has repeatedly communicated and discussed with the heads of relevant workshops and departments, and held a special workshop post optimization promotion meeting in September to clarify objectives and responsibilities, formulate implementation steps, and do a lot of preparatory work. At the kick-off meeting for the implementation of the large-scale inspection on October 31, Zhang Fengliang asked daye peak employees to recognize the current situation of serious cement overcapacity and cruel market competition, understand the necessity of implementing the large-scale inspection, and asked the workshop leaders to do a good job in training and guiding the employees, shorten the transition period, normalize the operation of the large-scale inspection as soon as possible, and at the same time, managers should also change their working ideas and concepts and do a good job in full-time, strengthen the inspection, overhaul and maintenance of the regular day shift, and find and solve the problems existing in the equipment and process in time.
2020
07-31
Two Cement Enterprises Start to Implement "Big Patrol Inspection"
With the change of the competition situation in the industry, the profit space of cement production enterprises has been greatly squeezed. Reducing costs and increasing efficiency and job optimization have become the inevitable choice to improve the enterprise's own development ability and enhance the core competitiveness. In accordance with the requirements of the group company to realize the transformation from extensive management to lean management, combined with the advanced experience of peer enterprises, recently, Yunnan peak, daye peak two enterprises have implemented "big inspection" to promote the overall optimization of posts. On November 1, daye peak post inspection officially started full operation, starting from the limestone storage yard at the source of the production line to the cement storage. the original 15 posts were merged, and the best experienced mechanics, electricians and post workers were transferred to form a large inspection class, which was mainly responsible for on-site emergency disposal and post routine maintenance to ensure the normal production of the whole production line. In order to ensure the smooth implementation of the large-scale inspection, daye peak management team has repeatedly communicated and discussed with the heads of relevant workshops and departments, and held a special workshop post optimization promotion meeting in September to clarify objectives and responsibilities, formulate implementation steps, and do a lot of preparatory work. At the kick-off meeting for the implementation of the large-scale inspection on October 31, Zhang Fengliang asked daye peak employees to recognize the current situation of serious cement overcapacity and cruel market competition, understand the necessity of implementing the large-scale inspection, and asked the workshop leaders to do a good job in training and guiding the employees, shorten the transition period, normalize the operation of the large-scale inspection as soon as possible, and at the same time, managers should also change their working ideas and concepts and do a good job in full-time, strengthen the inspection, overhaul and maintenance of the regular day shift, and find and solve the problems existing in the equipment and process in time.
2020
07-31
Jiang Xiaomeng: A Centennial Enterprise with Craftsman Spirit
Editor's note: A few days ago, the United Front Work Department of the Jinhua Municipal Party Committee, the Municipal Federation of Industry and Commerce and other units jointly launched a large-scale publicity campaign of "2016 Faith and Good Commerce". On October 18, Jinhua media reporters walked into the peak and conducted a collective interview with Chairman Jiang Xiaomeng. On October 21, the front page of Jinhua Daily published an article entitled "Jiang Xiaomeng: A Centennial Enterprise with Craftsman Spirit" written by its reporter Zhang Shuai. This newspaper is reproduced. Jiang Xiaomeng: With the spirit of craftsmanship and a century-old enterprise, speaking of the 58-year development history of Jianfeng Group, Chairman Jiang Xiaomeng's face is filled with passion and confidence. As one of Jinhua's oldest established companies, Spike is more qualified than most companies to imagine a hundred years. In the past 58 years, the peak has experienced ups and downs. Every time it encounters a major turning point, generations of "peak people" have opened a new chapter with tireless efforts and simple wisdom. A set of data shows the development trend: in the first half of this year, the peak achieved operating income of 1.103 billion yuan, an increase of 4.15 percent over the same period last year, and the net profit attributable to the owners of the parent company was 0.103 billion yuan, an increase of 12.9 percent over the same period last year. These data in the current weak domestic economic development, has become more prominent. Someone once asked Jiang Xiaomeng, what is the craftsman spirit? He answered that the essence of the craftsman spirit lies in firmness, steadfastness and professionalism, which is a spirit of excellence and refinement of what you do and the quality of your products. And these are the true portrayal of the peak standing for 58 years, and it is also a model for our "wushang" group to stick to industry, operate with integrity, and serve the country with industry. Looking back on history, through the sea, the formation of cement medicine
2020
07-31
In order to continue to thoroughly implement the spirit of General Secretary Xi Jinping's important speech and promote the healthy growth of people in the non-public sector of the economy and the healthy development of the non-public sector of the economy in Jinhua, the United Front work Department of the Jinhua Municipal CPC Committee, the Municipal Federation of Industry and Commerce and other units jointly carried out a large-scale publicity campaign of "2016 faith, righteousness and good business. On October 18, reporters from Jinhua TV and Jinhua Daily walked into the peak to fully understand the development process and business philosophy of the peak. Launched a series of reports on "Xinyi Good Wushang", aiming to vigorously promote the deeds of Jinhua's local outstanding enterprises, strengthen the construction of integrity in the non-public economy under the new situation, promote traditional virtues, establish new social fashions, actively practice the core values of socialism, and guide people in the industrial and commercial circles. Be a model of patriotism, dedication, law-abiding management, entrepreneurial innovation, and repaying the society; at the same time, through the required course, improve the internal governance structure and practice internal skills to make "patriotism, dedication, integrity, law-abiding, innovation, and contribution" become the new normal of the enterprise and the enterprise, thereby enhancing the corporate brand. In the face of the collective interview of Jinhua media reporters, Jiang Xiaomeng, chairman of the group company, introduced the arduous course of the development of peak entrepreneurship and the future development ideas of cement, medicine and health industries, and focused on the transformation and upgrading of enterprises, innovation and development, social welfare and other aspects. A series of work done. He said that Jianfeng has a history of 58 years since it started its business. It has always adhered to industry, integrity management, and industry to serve the country. In addition to actively assuming social responsibilities and advocating cadres and employees to participate in social welfare activities, it also strives to protect the natural environment and ecological resources in the process of production and operation,
2020
07-31
In order to continue to thoroughly implement the spirit of General Secretary Xi Jinping's important speech and promote the healthy growth of people in the non-public sector of the economy and the healthy development of the non-public sector of the economy in Jinhua, the United Front work Department of the Jinhua Municipal CPC Committee, the Municipal Federation of Industry and Commerce and other units jointly carried out a large-scale publicity campaign of "2016 faith, righteousness and good business. On October 18, reporters from Jinhua TV and Jinhua Daily walked into the peak to fully understand the development process and business philosophy of the peak. Launched a series of reports on "Xinyi Good Wushang", aiming to vigorously promote the deeds of Jinhua's local outstanding enterprises, strengthen the construction of integrity in the non-public economy under the new situation, promote traditional virtues, establish new social fashions, actively practice the core values of socialism, and guide people in the industrial and commercial circles. Be a model of patriotism, dedication, law-abiding management, entrepreneurial innovation, and repaying the society; at the same time, through the required course, improve the internal governance structure and practice internal skills to make "patriotism, dedication, integrity, law-abiding, innovation, and contribution" become the new normal of the enterprise and the enterprise, thereby enhancing the corporate brand. In the face of the collective interview of Jinhua media reporters, Jiang Xiaomeng, chairman of the group company, introduced the arduous course of the development of peak entrepreneurship and the future development ideas of cement, medicine and health industries, and focused on the transformation and upgrading of enterprises, innovation and development, social welfare and other aspects. A series of work done. He said that Jianfeng has a history of 58 years since it started its business. It has always adhered to industry, integrity management, and industry to serve the country. In addition to actively assuming social responsibilities and advocating cadres and employees to participate in social welfare activities, it also strives to protect the natural environment and ecological resources in the process of production and operation,
2020
07-31
In order to continue to thoroughly implement the spirit of General Secretary Xi Jinping's important speech and promote the healthy growth of people in the non-public sector of the economy and the healthy development of the non-public sector of the economy in Jinhua, the United Front work Department of the Jinhua Municipal CPC Committee, the Municipal Federation of Industry and Commerce and other units jointly carried out a large-scale publicity campaign of "2016 faith, righteousness and good business. On October 18, reporters from Jinhua TV and Jinhua Daily walked into the peak to fully understand the development process and business philosophy of the peak. Launched a series of reports on "Xinyi Good Wushang", aiming to vigorously promote the deeds of Jinhua's local outstanding enterprises, strengthen the construction of integrity in the non-public economy under the new situation, promote traditional virtues, establish new social fashions, actively practice the core values of socialism, and guide people in the industrial and commercial circles. Be a model of patriotism, dedication, law-abiding management, entrepreneurial innovation, and repaying the society; at the same time, through the required course, improve the internal governance structure and practice internal skills to make "patriotism, dedication, integrity, law-abiding, innovation, and contribution" become the new normal of the enterprise and the enterprise, thereby enhancing the corporate brand. In the face of the collective interview of Jinhua media reporters, Jiang Xiaomeng, chairman of the group company, introduced the arduous course of the development of peak entrepreneurship and the future development ideas of cement, medicine and health industries, and focused on the transformation and upgrading of enterprises, innovation and development, social welfare and other aspects. A series of work done. He said that Jianfeng has a history of 58 years since it started its business. It has always adhered to industry, integrity management, and industry to serve the country. In addition to actively assuming social responsibilities and advocating cadres and employees to participate in social welfare activities, it also strives to protect the natural environment and ecological resources in the process of production and operation,
2020
07-30
Contact Us
No. 88 Wujiang East Road, Jinhua City, Zhejiang Province, China
Tel: +86-579-82326868
Fax : +86-579-82324666
©2023 Zhejiang Jianfeng Group Co., Ltd. Powered by: www.300.cn SEO Business License
SAF Coolest v1.2 设置面板 SHJSS-AHDB-FSSQE-ZSW
无数据提示
Sorry, the current column has no content !
You can view other columns or return to Home Page