Small Molecule Targeted Drug Research Institute Established
Release time:
2020-08-14
Small Molecule Targeted Drug Research Institute Established
News 9# July 13 On the morning of the 9th, the listing ceremony of Anhui Jianfeng Beika Pharmaceutical Small Molecule Targeted Drug Research Institute was held in the Dongzhi Economic Development Zone of Anhui Province.
Dongzhi County Party Secretary Li Mingyue, County Mayor Sheng Guoxing, Chairman of the Group Company and Chairman of the Pharmaceutical Company Jiang Xiaomeng, and Lu Wei, founder of Shanghai Beika Pharmaceutical Company and professor of the Institute of Medicine of the Chinese Academy of Sciences, jointly unveiled the institute (right picture).
Sheng Guoxing County Chief pointed out in his speech at the listing site that the establishment of Anhui Jianfeng Beika Pharmaceutical Small Molecule Targeted Drug Research Institute is an attempt and exploration to deepen innovation drive and carry out industry-university-research cooperation. He hopes that Jianfeng Group will continue to increase investment in funds and talents, integrate scientific research resources, give full play to the innovative advantages of the research institute, and build the small molecule targeted drug research institute into a research institute with strong academic atmosphere, close industry-university-research cooperation, and remarkable scientific and technological achievements. He asked the Dongzhi Economic Development Zone Management Committee and relevant units directly under the county to make every effort to serve and ensure the construction and operation of the research institute, and through the joint efforts of all parties, the Dongzhi Economic Development Zone will be built into a highland of scientific and technological innovation, so that the park will bloom with science and technology. Flowers, bear the fruit of industry. Jiang Xiaomeng, chairman of
group company, delivered a speech at the listing ceremony of the research institute. He said that Shanghai North Carolina Pharmaceutical Company is a holding subsidiary of Jianfeng Group. It is a high-tech enterprise in Shanghai, a "specialized and new" technology enterprise in Shanghai, and a "Shanghai patent pilot enterprise". It has an academician expert workstation and Songjiang District "Enterprise Technology Center", and has a number of "Shanghai High-tech Achievement Transformation Project" results. The products mainly include intermediates such as small molecule targeted and alkaloid anti-tumor drugs. The company takes Shanghai Beika as the research and development and market highland, and takes Jianfeng Beika Pharmaceutical as the link of technology and variety transformation. The research and development results and industrialization results are produced and sold by two factories of Anhui Xinbeika Chemical and Anhui Zhongwang Pharmaceutical, and a small molecule targeted drug manufacturing base is built in Dongto Economic Development Zone. In order to better develop small molecule targeted drugs, with the assistance of Dongzhi County Party Committee and Economic Development Zone, a small molecule targeted drug research institute was established to speed up the progress of scientific and technological innovation and technological transformation, and realize the industrialization of small molecule targeted drug products as soon as possible. At the same time, the Small Molecule Targeted Drug Research Institute will also rely on the technical support of three academicians and experts of Jianfeng Pharmaceutical and four postdoctoral workstations, and cooperate with the Chinese Academy of Sciences, China Pharmaceutical University, Fudan University, Shanghai Molecular Therapy and New Drug Creation Engineering Technology Research Center and other scientific research institutions to establish long-term industry-university-research cooperation, in accordance with the principle of "innovation, creation, creation" and strive to create "green environmental protection, top technology, for the benefit of human health" high-end scientific research institutions. After the opening ceremony of
, Li Mingyue, Secretary of Dongzhi county Party committee, was interviewed by Jinhua Daily. While congratulating Jianfeng group on the 23rd anniversary of its establishment 60#, he said that Dongzhi county government and relevant departments will give maximum support and service to the small molecule targeted drug research institute, and ensure the construction and operation of the research institute, We hope that the Institute can give full play to its advantages and strive to achieve remarkable results as soon. (Ni Yingzhen Zhang Feifei)
1000 . The structure of small molecule drugs has good spatial dispersion, and its chemical properties determine its good pharmaceutical properties and pharmacokinetic properties. Small molecule drugs are usually signal transduction inhibitors, which can specifically block the signal transduction pathway necessary for tumor growth and proliferation, so as to achieve the purpose of treatment.
Targeting ). The purpose is to target the drug or its carrier at a specific lesion site and to accumulate or release the active ingredient at the target site. Targeted preparations can make the drug form a relatively high concentration in the target area, thereby improving the efficacy of the drug while inhibiting toxic side effects and reducing the damage to normal tissues and cells.
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Shanghai Bronze Award for Outstanding Invention Went in North Carolina
News from this newspaper The results of the 31st Shanghai Excellent Invention Trial jointly organized by the Shanghai Federation of Trade Unions, Shanghai Intellectual Property Office, Shanghai Municipal Committee of the Communist Youth League, Shanghai Science and Technology Association, and Shanghai Invention Association were evaluated a few days ago. The "Quality Improvement and Industrialization Optimization of Erlotinib Hydrochloride and Its Advanced Intermediates" declared by Technology Co., Ltd. won the bronze award. Erlotinib hydrochloride is a targeted therapy drug for the treatment of non-small cell lung cancer, which can prolong the survival time and improve the quality of life of lung cancer patients. It can target and specific sites of action to kill tumor cells, and has little impact on normal tissues. It belongs to the biological and new medical technology in the field of high-tech supported by the state. In this invention, 6,7-dimethoxyquinazoline -4-one, 4-chloro -6,7-di (2-methoxyethoxy) quinazoline and 3-aminophenylacetylene are important intermediates of erlotinib hydrochloride, which is also an important intermediate of icotinib hydrochloride, the first new anti-tumor drug of tinib in China. The invention designs and adopts a new synthesis process route, which can effectively reduce the cost of raw materials, the reactions are mostly aqueous phase reactions, energy consumption and three waste emissions are reduced by about 35%, industrialization conditions are optimized, product quality is improved, and it is applied to Industrialized mass production is conducive to the production of high-quality and low-cost erlotinib hydrochloride drugs and reduces the economic burden of patients. The Shanghai Excellent Invention Trial was founded in 1987. It is an important science and technology award approved by the Shanghai Municipal Government. It not only strongly promoted the majority of employees to carry out invention and creation activities based on their posts, but also improved the order.
2020
07-31
Jiang Xiaomeng was selected as one of the top ten news figures in the building materials industry. "China Building Materials" magazine published an exclusive interview in August. The 8th issue of 2019 "China Building Materials" magazine published a few days ago. In the "Exclusive Perspective" column, it published an exclusive interview with Jiang Xiaomeng, the top ten news figures in the building materials industry in 2018, the party secretary and chairman of the group company. The selection of the top ten news figures in the national building materials industry initiated by "China Building Materials" magazine has established nearly a hundred shining figures in the industry since 1999, which has attracted widespread attention in the industry. The selection of the top ten news figures in the building materials industry in 2018 is described as follows: Jiang Xiaomeng is a scholar and practical outstanding entrepreneur. In 2018, with his strategic thinking of insight into the future, he united and led cadres and employees at all levels of Jianfeng Group to actively adapt to the new economic normal, focusing on deepening supply-side structural reforms, the "Belt and Road" initiative, and vigorously advocating corporate transformation and upgrading and high-quality development. Work, seize opportunities, reform and innovate, and achieve historic new achievements in the development of the peak 60 years. The group's overall economic efficiency and development quality have been significantly improved. In recent years, under the leadership of Jiang Xiaomeng, Jianfeng Group has seized the opportunity to join forces with central enterprises to participate in the establishment of Southern Cement, effectively integrate the cement market in Zhejiang Province, optimize the allocation of cement industry resources, and greatly improve social and economic benefits. It has a positive and far-reaching impact on the supply-side structural reform and healthy development of the cement industry in Zhejiang Province. At the same time, the long-term layout of the peak group, strategically predict the direction of national development.
2020
07-31
Jianfeng Group started from a small cement plant with an annual output of 30000 tons in 1958. Through horizontal alliance with township enterprises, the formation of enterprise groups and the implementation of joint-stock reform, Jianfeng Group took the lead in listing in China's cement industry in 1993 and explored diversified operation. In 2007, Jianfeng joined hands with the central enterprise China Building Materials to participate in the establishment of Southern Cement, which strategically shifted the focus of the cement industry, and at the same time through enterprise mergers and technological innovation, the pharmaceutical industry is growing rapidly ...... Such a long history, in the industry has a good reputation of enterprises, Zhejiang Province, the earliest existing listed companies, its head is Jiang Xiaomeng. Focus on Industry Jiang Xiaomeng has spent nearly 40 years in Jinhua Cement Factory, the predecessor of Jianfeng Group. As a witness and promoter of the development and growth of the peak, Jiang Xiaomeng said that the sustained and steady development of the peak group benefits from the long-term focus on industry, which is the value orientation of the peak and the responsibility of the enterprise. Whether there was only a single cement industry in the early stage or the diversified development after listing, all the investment projects of the peak have not left the industry. With the continuous emergence of new economic formats, many people once suggested that the peak should be transferred to the "fashionable" and rewarding industries such as the Internet, but they were all rejected. Jiang Xiaomeng explained that it is necessary to use professional people to do professional things. Peak's years of experience, talents, and resource accumulation are all in industry. Although the new format is good, it is not necessarily suitable for peak development. Take cement as an example, even in the case of peak pharmaceutical has occupied the group.
2020
07-31
Jiang Xiaomeng was selected as one of the top ten news figures in the building materials industry. "China Building Materials" magazine published an exclusive interview in August. The 8th issue of 2019 "China Building Materials" magazine published a few days ago. In the "Exclusive Perspective" column, it published an exclusive interview with Jiang Xiaomeng, the top ten news figures in the building materials industry in 2018, the party secretary and chairman of the group company. The selection of the top ten news figures in the national building materials industry initiated by "China Building Materials" magazine has established nearly a hundred shining figures in the industry since 1999, which has attracted widespread attention in the industry. The selection of the top ten news figures in the building materials industry in 2018 is described as follows: Jiang Xiaomeng is a scholar and practical outstanding entrepreneur. In 2018, with his strategic thinking of insight into the future, he united and led cadres and employees at all levels of Jianfeng Group to actively adapt to the new economic normal, focusing on deepening supply-side structural reforms, the "Belt and Road" initiative, and vigorously advocating corporate transformation and upgrading and high-quality development. Work, seize opportunities, reform and innovate, and achieve historic new achievements in the development of the peak 60 years. The group's overall economic efficiency and development quality have been significantly improved. In recent years, under the leadership of Jiang Xiaomeng, Jianfeng Group has seized the opportunity to join forces with central enterprises to participate in the establishment of Southern Cement, effectively integrate the cement market in Zhejiang Province, optimize the allocation of cement industry resources, and greatly improve social and economic benefits. It has a positive and far-reaching impact on the supply-side structural reform and healthy development of the cement industry in Zhejiang Province. At the same time, the long-term layout of the peak group, strategically predict the direction of national development.
2020
07-31
Jiang Xiaomeng was selected as one of the top ten news figures in the building materials industry. "China Building Materials" magazine published an exclusive interview in August. The 8th issue of 2019 "China Building Materials" magazine published a few days ago. In the "Exclusive Perspective" column, it published an exclusive interview with Jiang Xiaomeng, the top ten news figures in the building materials industry in 2018, the party secretary and chairman of the group company. The selection of the top ten news figures in the national building materials industry initiated by "China Building Materials" magazine has established nearly a hundred shining figures in the industry since 1999, which has attracted widespread attention in the industry. The selection of the top ten news figures in the building materials industry in 2018 is described as follows: Jiang Xiaomeng is a scholar and practical outstanding entrepreneur. In 2018, with his strategic thinking of insight into the future, he united and led cadres and employees at all levels of Jianfeng Group to actively adapt to the new economic normal, focusing on deepening supply-side structural reforms, the "Belt and Road" initiative, and vigorously advocating corporate transformation and upgrading and high-quality development. Work, seize opportunities, reform and innovate, and achieve historic new achievements in the development of the peak 60 years. The group's overall economic efficiency and development quality have been significantly improved. In recent years, under the leadership of Jiang Xiaomeng, Jianfeng Group has seized the opportunity to join forces with central enterprises to participate in the establishment of Southern Cement, effectively integrate the cement market in Zhejiang Province, optimize the allocation of cement industry resources, and greatly improve social and economic benefits. It has a positive and far-reaching impact on the supply-side structural reform and healthy development of the cement industry in Zhejiang Province. At the same time, the long-term layout of the peak group, strategically predict the direction of national development.
2020
07-30
On August 29, the group company held the 11th meeting of the 10th board of directors of the company by means of communication, and deliberated and passed the semi annual report of Jianfeng group in 2019 and the amendment of internal control system of the company. In the first half of the year, the company focused on the general work policy of "innovation and reform, integration and improvement, scientific layout, and steady development", grasping the opportunities brought by economic structure optimization and industrial upgrading externally, continuously integrating resources internally, and improving the internal management system. Improve the efficiency of enterprise operation. In the first half of 2019, the company achieved total operating income of 1.686 billion billion yuan, an increase of 12.17 percent over the same period last year, and the net profit attributable to the owners of the parent company was 0.476 billion billion yuan, an increase of 57.55 percent over the same period last year. At the end of June 2019, the Company's total assets were $5.383 billion, up 9.82 from the beginning of the year, and its net assets were $3.817 billion, up 10.64 from the beginning of the year. In the first half of the year, the company made a new breakthrough in the expansion of cement business. The group company has completed the acquisition of 100 equity of Guizhou huangpinggu longmingchuan cement co., ltd. and continues to invest in the construction of its new dry cement production line with a daily output of 4500 tons of cement clinker (with waste heat power generation). Yunnan Jianfeng invested 5 million yuan to participate in the establishment of Yunnan Jianfeng Da Zhan Cement Co., Ltd., which plans to build a cement clinker production line in lameng county, Xishuangxian Dai autonomous prefecture by capacity replacement according to relevant national policies. The company's cement subsidiaries continue to carry out in-depth "three down three improve" activities, stable.
2020
07-31
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