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Small Molecule Targeted Drug Research Institute Established

Release time:

2020-08-14

Small Molecule Targeted Drug Research Institute Established

News 9# July 13 On the morning of the 9th, the listing ceremony of Anhui Jianfeng Beika Pharmaceutical Small Molecule Targeted Drug Research Institute was held in the Dongzhi Economic Development Zone of Anhui Province.

Dongzhi County Party Secretary Li Mingyue, County Mayor Sheng Guoxing, Chairman of the Group Company and Chairman of the Pharmaceutical Company Jiang Xiaomeng, and Lu Wei, founder of Shanghai Beika Pharmaceutical Company and professor of the Institute of Medicine of the Chinese Academy of Sciences, jointly unveiled the institute (right picture).

Sheng Guoxing County Chief pointed out in his speech at the listing site that the establishment of Anhui Jianfeng Beika Pharmaceutical Small Molecule Targeted Drug Research Institute is an attempt and exploration to deepen innovation drive and carry out industry-university-research cooperation. He hopes that Jianfeng Group will continue to increase investment in funds and talents, integrate scientific research resources, give full play to the innovative advantages of the research institute, and build the small molecule targeted drug research institute into a research institute with strong academic atmosphere, close industry-university-research cooperation, and remarkable scientific and technological achievements. He asked the Dongzhi Economic Development Zone Management Committee and relevant units directly under the county to make every effort to serve and ensure the construction and operation of the research institute, and through the joint efforts of all parties, the Dongzhi Economic Development Zone will be built into a highland of scientific and technological innovation, so that the park will bloom with science and technology. Flowers, bear the fruit of industry. Jiang Xiaomeng, chairman of

group company, delivered a speech at the listing ceremony of the research institute. He said that Shanghai North Carolina Pharmaceutical Company is a holding subsidiary of Jianfeng Group. It is a high-tech enterprise in Shanghai, a "specialized and new" technology enterprise in Shanghai, and a "Shanghai patent pilot enterprise". It has an academician expert workstation and Songjiang District "Enterprise Technology Center", and has a number of "Shanghai High-tech Achievement Transformation Project" results. The products mainly include intermediates such as small molecule targeted and alkaloid anti-tumor drugs. The company takes Shanghai Beika as the research and development and market highland, and takes Jianfeng Beika Pharmaceutical as the link of technology and variety transformation. The research and development results and industrialization results are produced and sold by two factories of Anhui Xinbeika Chemical and Anhui Zhongwang Pharmaceutical, and a small molecule targeted drug manufacturing base is built in Dongto Economic Development Zone. In order to better develop small molecule targeted drugs, with the assistance of Dongzhi County Party Committee and Economic Development Zone, a small molecule targeted drug research institute was established to speed up the progress of scientific and technological innovation and technological transformation, and realize the industrialization of small molecule targeted drug products as soon as possible. At the same time, the Small Molecule Targeted Drug Research Institute will also rely on the technical support of three academicians and experts of Jianfeng Pharmaceutical and four postdoctoral workstations, and cooperate with the Chinese Academy of Sciences, China Pharmaceutical University, Fudan University, Shanghai Molecular Therapy and New Drug Creation Engineering Technology Research Center and other scientific research institutions to establish long-term industry-university-research cooperation, in accordance with the principle of "innovation, creation, creation" and strive to create "green environmental protection, top technology, for the benefit of human health" high-end scientific research institutions. After the opening ceremony of

, Li Mingyue, Secretary of Dongzhi county Party committee, was interviewed by Jinhua Daily. While congratulating Jianfeng group on the 23rd anniversary of its establishment 60#, he said that Dongzhi county government and relevant departments will give maximum support and service to the small molecule targeted drug research institute, and ensure the construction and operation of the research institute, We hope that the Institute can give full play to its advantages and strive to achieve remarkable results as soon. (Ni Yingzhen Zhang Feifei)

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Small molecule drugs mainly refer to chemically synthesized drugs with molecular weight less than

1000 . The structure of small molecule drugs has good spatial dispersion, and its chemical properties determine its good pharmaceutical properties and pharmacokinetic properties. Small molecule drugs are usually signal transduction inhibitors, which can specifically block the signal transduction pathway necessary for tumor growth and proliferation, so as to achieve the purpose of treatment.

For ordinary drugs, only a very small part of them can really act on the lesion after entering the body. This is the root cause of restricting drug efficacy and leading to drug side effects. A targeted drug (also referred to as a targeting agent) refers to a drug or formulation thereof that is endowed with the ability to target (

Targeting ). The purpose is to target the drug or its carrier at a specific lesion site and to accumulate or release the active ingredient at the target site. Targeted preparations can make the drug form a relatively high concentration in the target area, thereby improving the efficacy of the drug while inhibiting toxic side effects and reducing the damage to normal tissues and cells.

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