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Behind the Luck.

Release time:

2020-08-14

"Luck"

Artificial Bezoar Workshop Reconstruction Documentary

After four months of intense work, 8# September 9 , the artificial bezoar technical renovation project of Qiubin Factory was successfully completed, 8 18 , 19 , 20 , the trial production of the first three batches of products was successfully completed. Yi Shengrong, director of the Akihama Factory, lamented, "We are lucky this time".

Good luck, this is of course a joke. To do such a big project well, luck alone is of course not enough. What really plays a decisive role is the seriousness and hard work of the project team members.

Pharmaceutical Company has many years of successful experience in producing artificial bezoar, but from the beginning of the project transformation, due to the use of raw materials, production process, process standards, and production scale are almost different, so the previous experience is not for them. Help, can only be explored from scratch through the efforts of participating construction personnel. From the beginning of the

project, the project team was formed by Yi Shengrong, director of Qiubin Factory, Yu Chengfeng, production technology department, Yan Xixia, workshop director, Fang Weiming, mechanic, and Tang Songnian, electrician. While ensuring normal production, the project began to transform. The civil engineering project of workshop

started in March 4 . The project team members divided their work according to their own fields. Fang Weiming and Tang Songnian, who were responsible for equipment selection, went to many equipment manufacturers to understand relevant information, make comparisons and prepare for bidding. Compared with the previous production, the requirements for environmental protection are higher now. When designing the artificial bezoar workshop, it was decided to adopt dust-free transportation. All equipment is connected through pipelines. In order to meet this requirement, most equipment must be customized from the manufacturer. Before the formal bidding of the equipment, the project team also held a special meeting to brainstorm and put forward opinions and suggestions on equipment selection according to the collected information and their own work experience. It has been suggested that corn starch is one of the main raw materials for the production of artificial bezoar. A lot of heat will be generated during the ball milling process. If the temperature is too high, the starch will stick together and affect the quality of the product. Although there is no requirement for this in the process standard, it can be related to the quality of the product, so when selecting the equipment, the equipment manufacturer is required to increase the cooling system for the heat dissipation problem of the ball mill. Fang Weiming said that it takes three months for general equipment manufacturers to obtain orders and provide products, but we only have more than one month, and the equipment is not stereotyped, so the two sides have communicated repeatedly many times.

Despite this, there were still some small "episodes" in the acceptance stage before the equipment entered the site ". There is a gap between the inlet and outlet of the equipment and the previous requirements, which will cause waste of raw materials. But because the construction period is very tight, the time nodes of each link are very close, if you can not enter the site on time, the whole project will be affected. This can be anxious for the project team. After communication and arrangement, it was finally decided to give the equipment manufacturer a week to revise it. After meeting the required requirements, the equipment was pulled over quickly. Other minor problems can only be to let the equipment manufacturer personnel come over and make on-site modifications.

In the trial production stage, in order to save costs, Qiubin Factory decided that the batch of products is 100 kg, while the design capacity of the equipment is 500 kg. There is no data that can be directly referred to for the process parameters such as ball mill speed, ball milling time and ball quantity. Before the trial, the members of the project team also consulted relevant production enterprises, however, the other party has only tried batch 300 kg, and has not succeeded. There are more than ten kinds of trial production schemes involved in the three parameters. Time and cost are not allowed to try multiple schemes. We can only rely on the collection and selection of indirect experience collected by project team members from various channels, and finally confirm the formation of the scheme decided to put into production. The trial production was an unexpected success. All the indexes of the three batches of trial production products passed the test. Moreover, the color, the most difficult index to control for artificial bezoar, was highly recognized by the sales agent.

The implementation of the whole project is relatively smooth, and there may be elements of luck, but behind this "luck", only the participants know how much effort and hardship they have put in. Cleaning the workshop equipment happens to be the hottest time. The weather has been more than 40 degrees for more than half a month, which makes the project team members unable to bear it. The workshop that has just been renovated is very dusty, but in order to ensure the cleaning quality, the air conditioner cannot be turned on, so it can only be cleaned under high temperature. Once out of the workshop, the whole person seems to have been soaked in water, and none of his body is dry. Moreover, his body is covered with dust. If there is something to do in the production workshop, he has to change clothes first.

Yan Xixia was impressed by one thing. The proportion and amount of balls in the ball mill will directly affect the product quality. For this reason, the two employees put 4 alumina balls of different sizes, totaling 2 tons, into small baskets one by one, and poured them into the ball mill with their bare hands for testing. The ball mill is large in size, and the feed port is above the machine. Employees holding the ball have to walk on a platform more than two meters high before they can pour in. If the ratio is not right, it has to be poured out again, cleaned, dried, and then poured in baskets again. This data alone has been tried for 3. four days. It goes up and down dozens of times a day. It is completely a physical job. Sometimes my hands shake after work. And sometimes afraid of miscounting the number of balls, employees squat down directly one by one.

Not only that, during the entire construction period from 4 to 7 February, Yu Chengfeng, Fang Weiming and Tang Songnian did not rest for a day and gave up their holidays. As long as the construction unit was present, they would have to be there. Finally, even the number of overtime days was not counted.

The end of the three batches of trial production products does not mean the end of this technological transformation project. They have a more important task, that is, to apply for GMP certification, and are now preparing for relevant materials. (Reporter Ni Yingzhen)

More information

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