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Behind the Luck.

Release time:

2020-08-14

"Luck"

Artificial Bezoar Workshop Reconstruction Documentary

After four months of intense work, 8# September 9 , the artificial bezoar technical renovation project of Qiubin Factory was successfully completed, 8 18 , 19 , 20 , the trial production of the first three batches of products was successfully completed. Yi Shengrong, director of the Akihama Factory, lamented, "We are lucky this time".

Good luck, this is of course a joke. To do such a big project well, luck alone is of course not enough. What really plays a decisive role is the seriousness and hard work of the project team members.

Pharmaceutical Company has many years of successful experience in producing artificial bezoar, but from the beginning of the project transformation, due to the use of raw materials, production process, process standards, and production scale are almost different, so the previous experience is not for them. Help, can only be explored from scratch through the efforts of participating construction personnel. From the beginning of the

project, the project team was formed by Yi Shengrong, director of Qiubin Factory, Yu Chengfeng, production technology department, Yan Xixia, workshop director, Fang Weiming, mechanic, and Tang Songnian, electrician. While ensuring normal production, the project began to transform. The civil engineering project of workshop

started in March 4 . The project team members divided their work according to their own fields. Fang Weiming and Tang Songnian, who were responsible for equipment selection, went to many equipment manufacturers to understand relevant information, make comparisons and prepare for bidding. Compared with the previous production, the requirements for environmental protection are higher now. When designing the artificial bezoar workshop, it was decided to adopt dust-free transportation. All equipment is connected through pipelines. In order to meet this requirement, most equipment must be customized from the manufacturer. Before the formal bidding of the equipment, the project team also held a special meeting to brainstorm and put forward opinions and suggestions on equipment selection according to the collected information and their own work experience. It has been suggested that corn starch is one of the main raw materials for the production of artificial bezoar. A lot of heat will be generated during the ball milling process. If the temperature is too high, the starch will stick together and affect the quality of the product. Although there is no requirement for this in the process standard, it can be related to the quality of the product, so when selecting the equipment, the equipment manufacturer is required to increase the cooling system for the heat dissipation problem of the ball mill. Fang Weiming said that it takes three months for general equipment manufacturers to obtain orders and provide products, but we only have more than one month, and the equipment is not stereotyped, so the two sides have communicated repeatedly many times.

Despite this, there were still some small "episodes" in the acceptance stage before the equipment entered the site ". There is a gap between the inlet and outlet of the equipment and the previous requirements, which will cause waste of raw materials. But because the construction period is very tight, the time nodes of each link are very close, if you can not enter the site on time, the whole project will be affected. This can be anxious for the project team. After communication and arrangement, it was finally decided to give the equipment manufacturer a week to revise it. After meeting the required requirements, the equipment was pulled over quickly. Other minor problems can only be to let the equipment manufacturer personnel come over and make on-site modifications.

In the trial production stage, in order to save costs, Qiubin Factory decided that the batch of products is 100 kg, while the design capacity of the equipment is 500 kg. There is no data that can be directly referred to for the process parameters such as ball mill speed, ball milling time and ball quantity. Before the trial, the members of the project team also consulted relevant production enterprises, however, the other party has only tried batch 300 kg, and has not succeeded. There are more than ten kinds of trial production schemes involved in the three parameters. Time and cost are not allowed to try multiple schemes. We can only rely on the collection and selection of indirect experience collected by project team members from various channels, and finally confirm the formation of the scheme decided to put into production. The trial production was an unexpected success. All the indexes of the three batches of trial production products passed the test. Moreover, the color, the most difficult index to control for artificial bezoar, was highly recognized by the sales agent.

The implementation of the whole project is relatively smooth, and there may be elements of luck, but behind this "luck", only the participants know how much effort and hardship they have put in. Cleaning the workshop equipment happens to be the hottest time. The weather has been more than 40 degrees for more than half a month, which makes the project team members unable to bear it. The workshop that has just been renovated is very dusty, but in order to ensure the cleaning quality, the air conditioner cannot be turned on, so it can only be cleaned under high temperature. Once out of the workshop, the whole person seems to have been soaked in water, and none of his body is dry. Moreover, his body is covered with dust. If there is something to do in the production workshop, he has to change clothes first.

Yan Xixia was impressed by one thing. The proportion and amount of balls in the ball mill will directly affect the product quality. For this reason, the two employees put 4 alumina balls of different sizes, totaling 2 tons, into small baskets one by one, and poured them into the ball mill with their bare hands for testing. The ball mill is large in size, and the feed port is above the machine. Employees holding the ball have to walk on a platform more than two meters high before they can pour in. If the ratio is not right, it has to be poured out again, cleaned, dried, and then poured in baskets again. This data alone has been tried for 3. four days. It goes up and down dozens of times a day. It is completely a physical job. Sometimes my hands shake after work. And sometimes afraid of miscounting the number of balls, employees squat down directly one by one.

Not only that, during the entire construction period from 4 to 7 February, Yu Chengfeng, Fang Weiming and Tang Songnian did not rest for a day and gave up their holidays. As long as the construction unit was present, they would have to be there. Finally, even the number of overtime days was not counted.

The end of the three batches of trial production products does not mean the end of this technological transformation project. They have a more important task, that is, to apply for GMP certification, and are now preparing for relevant materials. (Reporter Ni Yingzhen)

More information

Spike New Drug Approved for Registration

On April 16, Jianfeng Pharmaceutical Company received the approval and issuance of Olopatadine Hydrochloride Eye Drops "Drug Registration Approval" (approval number: 2019S00296) approved by the State Drug Administration. Olopatadine hydrochloride eye drops is mainly used to treat the signs and symptoms of allergic conjunctivitis. It is a mast cell stabilizer and a relatively selective histamine H1-receptor antagonist. It can inhibit type I immediate allergic reactions in vivo and in vitro experiments. At present, the product has been included in the "National Basic Medical Insurance, Work Injury Insurance and Maternity Insurance Drug Catalog (2017 Edition)" and classified as Class B. According to the relevant data of IMS database, in 2018, the global sales of olopatadine hydrochloride eye drops were about 0.37 billion US dollars, and the sales in China were about 10.232 million US dollars. Spike Pharmaceuticals already has the corresponding production line, this time to obtain the registration approval, marking Spike Pharmaceuticals has the qualification to carry out the production and sales of olopatadine hydrochloride eye drops, will further enrich the product line of Spike Pharmaceuticals, help to enhance the competitiveness of the company's pharmaceutical business. (Xia Yingpin)

2020

07-22

Peak International Trade was rated as "excellent delivery warehouse" by the big business"

On April 12, the 2019 Dalian Commodity Exchange Industrial Products Delivery Work Summary Meeting was held in Dalian. Jianfeng International Trading Company was rated as "2018 (Industrial Products) Excellent Delivery Warehouse" and Ruan Weihang, an employee of the International Trading Company, was rated as "2018 (Industrial Products) Excellent Futures Specialist in Designated Delivery Warehouse". The delivery link is the bridge link between the futures and cash markets, an important area of risk prevention and control in the futures market, and a strong guarantee for the smooth operation and function of the market. Since obtaining the qualification of PVC delivery warehouse in 2009, the chemical warehousing and logistics business of international trading company has developed steadily. In terms of management, the international trading company strictly follows the various systems of the Dalian Commodity Exchange to implement warehouse-in and warehouse-in management. The management level has been improved year by year. Broken packages have been handled on the spot, and the loss of goods has been greatly reduced. The management goal of daily clearing has been achieved, and standardized operations have been achieved; in terms of business marketing, the futures business has driven the gradual development and growth of the spot business, futures varieties have developed from a single PVC variety to four varieties of PVC, PP, PE and plywood. The business volume has increased year by year and has exceeded 500000 tons. The operation volume can exceed 2500 tons/day; In terms of customer service, from zero experience in futures business to now, customer reputation has increased year by year, and customer complaints have gradually decreased. The annual excellent delivery warehouse of the judges is the full affirmation of Dalian Commodity Exchange on the functions of international trading companies, market satisfaction, futures management level and standardization of warehouse daily management. Lou Chunming, general manager of the international trading company, said that the international trading company will implement

2020

07-31

Spike New Drug Approved for Registration

2020

07-30

Peak Cement Won the Bid for National Key Project Daye Peak Becomes Huang-Huang Railway Supplier

On March 19, Daye Jianfeng Cement Company officially received a notice from China Railway Construction Material Collection Center that the company was shortlisted for the new Huang (Mei) Huang (Zhou) railway project in the Hubei section of the Shanghai-Chengdu high-speed railway along the Yangtze River in the second place, and obtained the right to supply the 6th package of cement. This is the first stick undertaken by Daye Jianfeng in 2019, and it is also the second time to enter the high-speed rail project after the Wu (Han) Jiu (Jiang) high-speed rail. The Huanghuang high-speed railway is a component of the "eight vertical and eight horizontal" high-speed railway network in the "National Medium and Long-term Railway Network Plan". It is a component of the Wuhan-Hangzhou and Beijing-Hong Kong-Kowloon high-speed railway network. It has a total length of 125 kilometers and a design speed of 350 kilometers per hour. It will start construction at the end of 2018. It will be opened to traffic in 2021. In addition to the characteristics of large demand for high-speed railway and highway projects, the project time span is long and the product quality requirements are high, especially the high-speed railway project has extremely strict requirements on the alkali content of cement. After participating in the bidding, Yuan Xianming, executive deputy general manager of Daye Peak, organized production, quality control, procurement and other relevant departments for many times to carry out tests on the production of low-alkali cement and adjust the proportion of raw materials. The quality control department also sent samples to the provincial professional inspection department for comparative inspection to ensure product stability. The marketing department carefully checked the details of the tender, strictly checked and repeatedly deduced the bid price. Finally, with the full cooperation of all departments, the successful bidding was passed, finalist Huang-Huang high-speed rail project. It is understood that as the country continues to increase investment in infrastructure transportation construction, daye peak adjusted its work direction at the end of 2018, requiring marketing work in 2019 to focus on key projects.

2020

07-31

Daye Peak Opens "Standard Year"

After the 2019 overhaul ended in early March, Daye Jianfeng Cement Company immediately launched the "Standard Year" activity to carry out standardized rectification in view of a series of defects and problems in the daily management process. The goal of the "Standard Year" activity is to target specific issues that affect employees' work efficiency and safe and environmentally friendly production. Through the formulation of institutionalized work standards, further standardize employees' various operations, improve operational efficiency, and improve grassroots management execution, so as to achieve The purpose of improving the company's image, reducing costs, improving efficiency, and increasing benefits. In order to ensure the smooth progress of the activities, daye peak has set up a promotion team headed by general manager Zhang fengliang to be responsible for the overall promotion of the "standard year" activities, mainly including revising the activity plan, summarizing the standardized implementation standards of various departments, implementing the plan, supervising the implementation progress, evaluating the implementation effect, collecting suggestions and opinions in the implementation process, etc. Based on the foundation, aiming at the details and solving problems is a major feature of Daye peak's "standard year" activity. For example, the "Flange Sealing Operation Standard", which is currently being tried out, not only puts forward standardization requirements for such a "trivial matter" in equipment management as flange sealing, but also attaches "model" photos to make it clear to mechanics What should be done and what should be done. However, this "small standard" aims at three problems: leakage at the production site, extensive mechanic work and waste of materials. Once it becomes the behavior habit of employees, the hygiene and cost control at the production site are bound to be improved. It is understood that Daye peak "standard year" activities plan to continue for three years to promote, activities

2020

07-22

Daye Peak Opens "Standard Year"

2020

07-31

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